Right in the middle of the V&A Waterfront, the One&Only Cape Town overlooks the marina with views of Table Mountain and does urban chic with world-class amenities. The hotel spa has its very own quarter-acre (1,000 m²) private island, and dining options include a Nobu and a chic brasserie. Although all suites are spacious and done up in sleek South African style, luxury travelers may want to look to the Champagne Suite by Dom Pérignon, a carefully curated experience and the first of its kind in Africa.

oneandonlyresorts.com